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GABA stands for gamma-aminobutyric acid, is the product of a biochemical decarboxylation reaction of glutamic acid by the vitamin pyridoxal, as well as from decarboxylase (GAD).
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GABA is required as an inhibitory neurotransmitter to block the transmission of an impulse from one cell to another in the central nervous system, which prevents over-firing of the nerve cells.
It is also used for brain metabolism and to treat both epilepsy and hypertension where it is thought to induce tranquility in individuals who have a high activity of manic behavior and acute agitation.
In combination with inositol and nicotinamide it helps with blocking anxiety and stress related impulses from reaching the motor centers of the brain.
Gamma-Aminobutyric Acid can be used to calm a person, much like tranquilizers, but without the possibility of addiction.
It has been suggested that a shortage of GABA may cause panic attacks, since an intake of tranquilizers can increase the level of GABA in the body. GABA may also be effective in treating PMS in women.
The dosage listed is the Recommended Daily Allowance (RDA), but be aware that this dosage is the minimum that you require per day, to ward off serious deficiency of this particular nutrient. In the therapeutic use of this nutrient, the dosage is usually increased considerably, but the toxicity level must be kept in mind.
Dosage has not been established, but it is interesting to note that some research suggests that the supplement Kava (kava is a herbal root used as a supplement) causes more GABA receptors to form in the brain.
Toxic levels have not been established, but very high intake of GABA may cause anxiety, tingling of extremities, shortness of breath as well as a numb feeling around the mouth.
It is sometimes used as sexual a stimulant because of its relaxing capabilities, as well as with prostate problems, since it also assists with the release of sex hormones.
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