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Hydroxyproline amino acid information pageHydroxyproline can be synthesized in the body, making it a non-essential amino acid and is used nearly exclusively in structural proteins including collagen and connective tissue. As information is not plentiful on this nutrient, our page is also very short.
This amino acid is not incorporated into collagen during biosynthesis at the ribosome, but is formed from proline by a post-translational modification by an enzymatic hydroxylation reaction. Non-hydroxylated collagen is commonly termed pro-collagen. It was first isolated in 1902 from gelatin. Excretion of abnormal quantities of hydroxyproline is a symptom of the connective-tissue disease called Marfan's syndrome.
Amino acidsProducts
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